EVIDENCE-BASED
47,000+ trials analyzed
59,000+ interactions
Not FDA evaluated

What Actually Works for Better Skin?

The beauty supplement market promises glowing skin from the inside out. Some of it works. Most of it doesn't. Here's what research actually supports.

TL;DR

Best evidence: Collagen peptides (8-12 weeks), Omega-3 (anti-inflammatory), Vitamin C (if deficient). Moderate evidence: Zinc (for acne), Biotin (only if deficient). Doesn't work: Most "beauty blends," high-dose biotin for normal hair/nails.

A

Strong Evidence

Collagen Peptides
5-10g daily15 studies

Improves skin elasticity and hydration

8-12 weeks

Note: Works, but results are modest. Not miraculous.

Omega-3 Fatty Acids
1-2g EPA+DHA daily12 studies

Reduces inflammation, may improve acne and dry skin

8-12 weeks

Note: Anti-inflammatory benefit is real.

Vitamin C
500-1000mg daily20 studies

Essential for collagen synthesis

4-8 weeks

Note: Food sources often sufficient. Supplements if diet is poor.

B

Moderate Evidence (Condition-Specific)

Zinc
15-30mg daily10 studies

May help inflammatory acne

8-12 weeks

Note: Works best if deficient. Common in acne sufferers.

Vitamin E
15mg daily8 studies

Antioxidant, may help with UV damage recovery

8-12 weeks

Note: Food sources preferred. High-dose supplements risky.

Astaxanthin
4-12mg daily6 studies

Antioxidant, may reduce UV-induced skin damage

8-12 weeks

Note: Promising but limited human data.

F

Limited Evidence / Overhyped

Only helps if you're actually deficient (rare)

N/A

Note: Most people get enough from diet. Excess doesn't help.

Hyaluronic Acid (Oral)
Various3 studies

Limited evidence it reaches skin after oral intake

N/A

Note: Topical HA is proven. Oral is questionable.

Beauty Blends
Various

Usually underdosed collagen with random antioxidants

N/A

Note: Check doses. Usually too low to work.

Real Talk

Most of what affects your skin is external: sun exposure, skincare routine, and genetics. Supplements work from the inside, which is slower and subtler. Collagen has real evidence. Omega-3 helps inflammation. Everything else is marginal.

What Else Actually Helps

  • Sunscreen. the single best anti-aging intervention
  • Retinoids. proven to reduce wrinkles and improve texture
  • Hydration. drink water, use moisturizer
  • Sleep. skin repairs during sleep
  • Don't smoke. accelerates skin aging dramatically

The Bottom Line

Collagen peptides work if you're patient (8-12 weeks). Omega-3 helps inflammation. Sunscreen matters more than any supplement. Skip the $80 "beauty blends."

Related Guides

About this information: Our recommendations draw from peer-reviewed clinical trials, systematic reviews, and the same medical databases your doctor uses. These statements have not been evaluated by the FDA. Supplements are not intended to diagnose, treat, cure, or prevent any disease.

Moderate Evidence

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