Best Supplements for Men

47,000+ trials analyzed
59,000+ interactions
Not FDA evaluated

Evidence-based supplement guide for men's health priorities: testosterone support, heart health, muscle maintenance, and prostate wellness.

Quick Answer

Top 3 supplements for men: Vitamin D3, Magnesium, Omega-3 (EPA/DHA). These address the most common deficiencies and health concerns for this group.

Heart health
Testosterone levels
Muscle mass
Prostate health
Energy and performance

Common Deficiencies in Men

Understanding which nutrients men commonly lack helps prioritize supplementation. These deficiencies are backed by population studies and clinical research.
NutrientPrevalenceWhy It Happens
Vitamin D~40% deficientIndoor work, less sun exposure
Magnesium~60% inadequateSweating, stress, and alcohol deplete stores
ZincCommon in active menLost through sweat; critical for testosterone
Omega-3Most don't get enoughLow fish intake in Western diets

Essential Supplements

These supplements have strong evidence for men and address the most common nutritional gaps. Consider these your foundation.
#1Vitamin D3Strong Evidence

Supports testosterone, mood, and immune function

Dose:2000-5000 IU daily
#2MagnesiumStrong Evidence

Testosterone, sleep, and muscle recovery

Dose:400-500mg daily
#3Omega-3 (EPA/DHA)Strong Evidence

Heart health - men have higher cardiovascular risk

Dose:2000-3000mg EPA+DHA

Recommended Supplements

These supplements offer additional benefits for men based on specific needs and goals. Not everyone needs all of these - prioritize based on your individual situation.
Zincstrong

Testosterone production and immune support

Dose: 15-30mg daily
Creatinestrong

Muscle strength, power, and cognitive function

Dose: 5g daily
Ashwagandhamoderate

Stress, cortisol, and testosterone support

Dose: 300-600mg KSM-66

Worth Considering

Saw Palmetto

Prostate health after age 40

What to Avoid or Limit

  • High-dose Vitamin E. Studies show increased prostate cancer risk at 400 IU+
  • Excessive Zinc (50mg+). Can lower HDL cholesterol and cause copper deficiency

Lifestyle Factors

Supplements work best when combined with lifestyle awareness. These factors significantly affect nutrient needs for men.
Alcohol significantly depletes B vitamins, magnesium, and zinc
High-protein diets increase magnesium requirements
Intense exercise increases zinc and magnesium losses through sweat
Stress elevates cortisol which competes with testosterone

Special Considerations

  • 1.Get testosterone and vitamin D tested before supplementing
  • 2.Combine vitamin D with K2 for cardiovascular benefits
  • 3.Zinc should be taken with copper (8:1 ratio) long-term
  • 4.Creatine is the most researched sports supplement with excellent safety

Frequently Asked Questions

Vitamin D (if deficient), zinc, magnesium, and ashwagandha can support healthy testosterone levels. However, they won't raise levels beyond your natural range - they help optimize what you're capable of producing.

Related Guides

About this information: Our recommendations draw from peer-reviewed clinical trials, systematic reviews, and the same medical databases your doctor uses. These statements have not been evaluated by the FDA. Supplements are not intended to diagnose, treat, cure, or prevent any disease.

Moderate Evidence

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