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How to Build Your First Supplement Stack (Without Wasting Money)

Most people either take too many supplements or the wrong ones. Here's how to build a foundation stack that actually works.

CS
Research Team
Check Supplement
December 25, 2025
How to Build Your First Supplement Stack (Without Wasting Money)
Quick Answer~ It Depends

How do I build a good supplement stack?

Start with Vitamin D, Magnesium, and Omega-3s as your foundation. Add targeted supplements based on specific goals like energy, sleep, or focus.

  • Foundation first: D, Mg, Omega-3
  • Add based on goals
  • Check interactions
Read full explanation
You've decided to start taking supplements. Maybe you want more energy, better sleep, or just to fill nutritional gaps. The problem? Walk into any health store and you're hit with 500 different bottles making wild claims.
01

Start With the Foundations

Before buying anything fancy, cover your bases. These are the supplements that benefit the widest range of people based on actual research:

Vitamin D - Unless you live at the equator and work outside, you're probably low. 2000-5000 IU daily for most people.

Magnesium - About 50% of Americans don't get enough. Start with 200-400mg glycinate or citrate at night.

Omega-3s - Fish oil or algae oil. 1-2g of combined EPA/DHA daily.

Quick Tips

  • Get your Vitamin D levels tested first if possible
  • Take magnesium at night - it helps with sleep
  • Keep fish oil in the fridge to prevent oxidation
02

Add Based on Your Goals

Once you have the foundations, add supplements targeted to what you actually want to achieve:

For Energy: Creatine, B-vitamins if deficient, Iron if tested low.

For Sleep: Magnesium, L-theanine, Glycine.

For Focus: Alpha-GPC, Lion's Mane, Bacopa.

Quick Tips

  • Match supplements to specific goals
  • Start with one new supplement at a time
03

Check for Interactions

Some supplements cancel each other out, some compete for absorption. Calcium and magnesium compete for absorption - take them at different times.

Quick Tips

  • Use a stack checker to find conflicts
  • Space out competing supplements by 2-4 hours
04

Quality Matters More Than Brand

Third-party testing is the gold standard. Look for USP, NSF, or Informed Sport certifications.

Quick Tips

  • Look for third-party certifications
  • Research bioavailability of forms

Key Takeaways

Building a supplement stack isn't about taking more - it's about taking the right things for your body.

Ingredients Mentioned

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Vitamin DMagnesiumOmega-3
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