Metformin (Longevity Discussion)
Solid evidence for blood sugar. Not a miracle worker, but genuinely useful for the right person.
Verdict
7/10 Solid
Evidence
Grade B / 100+ Studies
The No-BS Summary
8 things. 60 seconds. Everything you need.
WHAT IT DOES
Diabetes drug with longevity potential. TAME trial.
DOES IT WORK?
7/10 Solid. Good pick. Prescription diabetes drug. AMPK activator. Large TAME trial underway for longevity. May interfere with exercise adaptations. Off-label use growing.
HOW MUCH TO TAKE
See product label
COST
Budget-friendly. $20-35/month for quality brands.
FIRST 24 HOURS
Don't expect miracles on day one. It's building in your system.
AFTER A FEW WEEKS
Give it 4-8 weeks for full effects. Patience pays.
SAFETY
Safe for most people. No red flags at normal doses.
HOW IT FEELS
May cause GI issues initially. Blood sugar stabilizes.
QUICK ANSWERS
+ 4 more questions
DOSE-RESPONSE CURVE
How effective is creatine monohydrate at different doses? Here's what the research shows.