What is the best vitamins for fatigue?

The best vitamins for fatigue depends on individual factors, but top evidence-based options include supplements with clinical backing for this specific use case. Our ranking considers efficacy, safety, and value.

How much vitamins should I take for fatigue?

Optimal dosing for fatigue varies by specific supplement. Clinical studies typically use evidence-based doses that differ from standard recommendations. See our detailed dosing guide below.

How long does it take for vitamins to help with fatigue?

Onset time varies: some supplements show effects within days, while others require 4-8 weeks of consistent use. We break down expected timelines for each option.

Best Vitamins for Fatigue

Evidence-based ranking of vitamins options for fatigue. Updated February 2026.

#1 PickBased on 12+ studies

Vitamins

Score: 8.5/10. Those looking to support fatigue

Follow label directions 4-8 weeks $$

Complete Rankings

VitaminsResearch Pending

8.5

Those looking to support fatigue

PROS

May support fatigue
Generally safe
Worth considering

CONS

• Limited specific research
• Individual results vary

Dose: Follow label directionsTiming: Consistent daily useOnset: 4-8 weeksCost: $$

Full analysis →

Quick Comparison

Supplement	Score	Dose	Onset	Cost
Vitamins	8.5	Follow label directions	4-8 weeks	$$

Common Questions

Based on clinical evidence, Vitamins ranks as the top choice for fatigue. It scores 8.5/10 due to May support fatigue and Generally safe. Those looking to support fatigue.

Fatigue Stack Guide

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How We Rank

Our rankings are based on: clinical evidence quality (40%), effect size (30%), safety profile (20%), and value (10%). We analyze meta-analyses and RCTs from PubMed, Cochrane, and peer-reviewed journals.

Disclaimer: This is educational content, not medical advice. Consult a healthcare provider before starting any supplement regimen.