EVIDENCE-BASED
47,000+ trials analyzed
59,000+ interactions
Not FDA evaluated

What Actually Works for Focus?

The "nootropics" market is 90% hype. Here's what has actual research for improving focus, and what's just expensive placebo.

TL;DR

Best evidence: Caffeine + L-theanine, Creatine (for cognitive fatigue). Moderate evidence: Omega-3 (long-term), Bacopa (long-term). Limited evidence: Lion's Mane, Ginkgo. Doesn't work: Most nootropic stacks, racetams (inconsistent), "limitless" pills.

A

Strong Evidence

Caffeine + L-Theanine
100mg caffeine + 200mg L-theanine15 studies

Focus without jitters, improved attention

30-60 minutes

Note: This combo is well-studied and works

Creatine
5g daily10 studies

Helps cognitive function under sleep deprivation and stress

1-2 weeks loading

Note: Brain uses ATP too. Creatine helps.

B

Moderate Evidence (Long-Term)

Omega-3 (DHA)
1-2g EPA+DHA daily20 studies

Supports brain structure, may help attention long-term

8-12 weeks

Note: Not a quick fix. Brain health maintenance.

Bacopa Monnieri
300-450mg daily8 studies

Improves memory and learning over time

8-12 weeks

Note: Takes months to work. Most people give up too soon.

C

Limited/Inconsistent Evidence

Lion's Mane
500-1000mg daily4 studies

NGF support, promising but human data limited

4-8 weeks

Note: Interesting mechanism, needs more human trials

Ginkgo Biloba
120-240mg daily12 studies

May help in elderly, less clear for young adults

4-6 weeks

Note: Mixed results across studies

F

Doesn't Work / Overhyped

Most "Nootropic Stacks"
Various

Usually underdosed ingredients with big marketing

N/A

Note: Check individual doses. Usually too low to work.

Racetams (Piracetam, etc.)
Various6 studies

Decades of research, still unclear if they work in healthy adults

N/A

Note: Original nootropic, but evidence is disappointing

Real Talk

There's no "Limitless" pill. Sorry. The best cognitive enhancer is sleep. After that, caffeine + L-theanine is the most reliable combo. Everything else is either long-term brain support (omega-3) or inconsistent at best.

What Else Actually Helps

  • Sleep. your brain literally cleans itself during sleep
  • Exercise. increases BDNF, genuinely helps cognition
  • Reduce digital distraction. attention is trainable
  • Blood sugar stability. crashes destroy focus

The Bottom Line

Caffeine + L-theanine is the only "nootropic" that reliably works in the short term. For long-term brain health, omega-3 and good sleep beat any pill.

Related Guides

About this information: Our recommendations draw from peer-reviewed clinical trials, systematic reviews, and the same medical databases your doctor uses. These statements have not been evaluated by the FDA. Supplements are not intended to diagnose, treat, cure, or prevent any disease.

Moderate Evidence

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