Best Supplements for Pregnancy

What you actually need, trimester by trimester

Pregnancy supplements aren't optional. They're critical. Folate prevents neural tube defects. Iron supports the massive increase in blood volume. DHA builds baby's brain. Here's what you need and when.

Essential (Non-Negotiable)

Effective Dose400-800mcg daily, ideally started 3 months before conception
Time to EffectPreventive, from conception

Neural tube defects occur in the first 28 days, often before you know you're pregnant. Folate is the single most important supplement for pregnancy. Methylfolate may be better for those with MTHFR variants.

Best for:All pregnant womenWomen trying to conceive
Iron10/10
Effective Dose27-30mg daily in prenatal, more if anemic
Time to EffectOngoing

Your blood volume increases by 50% during pregnancy. Iron demand skyrockets. Deficiency increases risk of preterm birth and low birth weight. Take with vitamin C for absorption.

Best for:All pregnant women
Effective Dose200-300mg DHA daily minimum, 500mg+ optimal
Time to EffectOngoing, especially third trimester

DHA is a structural component of the baby's brain and retina. Peak demand is in third trimester. Most prenatals don't include enough. Consider a separate DHA supplement.

Best for:Brain and eye development

Also Important

Effective Dose2000-4000 IU daily
Time to EffectOngoing

Supports calcium absorption for baby's bone development. Deficiency linked to preeclampsia, gestational diabetes, and preterm birth. Most prenatals contain only 400-600 IU, which is likely insufficient.

Best for:All pregnant womenThose with limited sun exposure
Choline7.5/10
Effective Dose450-550mg daily
Time to EffectOngoing

Critical for brain development, similar to folate. Most prenatals don't include it, and most women don't get enough from diet. Eggs are the best food source.

Best for:Brain developmentThose who don't eat eggs
Iodine8/10
Effective Dose150-220mcg daily
Time to EffectOngoing

Essential for thyroid function and baby's brain development. Deficiency is common and serious. Make sure your prenatal includes it, or supplement separately.

Best for:All pregnant women

Beyond Supplements

  • Start prenatal vitamins before conception if possible
  • Morning sickness? Ginger and vitamin B6 can help
  • Avoid high-dose vitamin A (retinol form) which can cause birth defects
  • Fish is good for pregnancy but limit high-mercury types
  • Prenatal quality matters. Third-party testing recommended.

Note: Pregnancy nutrition is critical for both mother and baby. Work with your OB/GYN or midwife on supplement recommendations tailored to your specific situation.

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Track your prenatal regimen

Keep all your pregnancy supplements organized and monitor your intake.

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