Check Supplement
Check My StackMy Health
All Products
T
Thorne
SPECIMEN #THORNE-D
Verified
MOODThorne

Deproloft-HF

Multi-pathway mood support: 5-HTP for serotonin, saffron for mood, rhodiola for stress resilience, chromium for blood sugar stability. DO NOT take with SSRIs (serotonin syndrome risk). For people not on antidepressants wanting natural mood support.

7.8/10
VERY GOOD

Multi-pathway mood support: 5-HTP for serotonin, saffron (affron) for mood, rhodiola for stress resilience, chromium for blood sugar mood connection. Thoughtful practitioner formulation.

4 ingredientsCapsules30 servings
We'd recommend this
Evidence
8.0
Dosing
7.0
Synergy
9.0
Check My Stack
Whenmorning

Mood support throughout the day. Some take a second dose at lunch.

Foodwith food

5-HTP can cause nausea on empty stomach.

SafetySome cautions

DO NOT combine with SSRIs, SNRIs, or MAO inhibitors. 5-HTP + serotonergic drugs = serotonin syndrome risk.

ResearchStrong evidence

Each ingredient has individual mood research. 5-HTP + saffron + rhodiola is a well-reasoned combination.

What We Like

  • 5-HTP directly increases serotonin synthesis.
  • Saffron (affron) has clinical trials for mood.
  • Rhodiola at 200mg for stress resilience.
  • Chromium for blood sugar-mood connection.
  • Multi-pathway approach.

Watch Out For

  • 5-HTP at 50mg is conservative (studies use 100-300mg).
  • Saffron at 15mg is half the studied dose (30mg).
  • Must not combine 5-HTP with SSRIs (serotonin syndrome risk).

Ingredient Breakdown

4 underdosed
Clinical Adequate Underdosed Overdosed|Bar = % of clinical dose
IngredientDoseStatusvs. Clinical
5-HTP9.0

from Griffonia simplicifolia

50 mgUNDERDOSED
33%
50 mg

of 150mg

UNDERDOSED
33%
Saffron Extract

affron, 3.5% Lepticrosalides

15 mgUNDERDOSED
50%
15 mg

of 30mg

UNDERDOSED
50%
Rhodiola9.0

3% Rosavins

200 mgUNDERDOSED
50%
200 mg

of 400mg

UNDERDOSED
50%
Chromium10.0

Chromium Picolinate

100 mcgUNDERDOSED
50%
100 mcg

of 200mcg

UNDERDOSED
50%
In our database (click to learn more) Not yet reviewed

Our Analysis

Best For

People with mild mood concerns not on antidepressants.Seasonal mood changes.Those wanting multi-pathway natural mood support.

Skip This If

ANYONE on SSRIs, SNRIs, or MAO inhibitors.People with severe depression (see a doctor).

Time to Feel

5-HTP: 1-2 weeks. Full formula: 4-8 weeks.

Value

GOOD

How to take: Can use daily. Monitor mood response.

Personalized Deep Analysis

See exactly how this fits your health profile. What works for you, what doesn't, and whether you're getting your money's worth.

Unlock with Pro

Taking other supplements too?

Check your full stack for interactions, redundancies, and gaps. Takes 30 seconds.

Check My Stack
0 views