Rapamycin (Sirolimus)

Solid evidence for mtor inhibition. Not a miracle worker, but genuinely useful for the right person.

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Verdict

7/10 Solid

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Evidence

Grade B / 100+ Studies

The No-BS Summary

8 things. 60 seconds. Everything you need.

1

WHAT IT DOES

The immunosuppressant being studied for longevity

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2

DOES IT WORK?

7/10 Solid. Good pick. FDA-approved immunosuppressant. Longevity interest due to lifespan extension in animals. Requires medical supervision. Intermittent dosing studied.

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3

HOW MUCH TO TAKE

Follow label

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4

COST

$25-60/month depending on brand and form.

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5

FIRST 24 HOURS

Don't expect miracles on day one. It's building in your system.

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6

AFTER A FEW WEEKS

Most people notice something by week 2-3.

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7

SAFETY

Safe for most people. No red flags at normal doses.

8

HOW IT FEELS

Not for self-experimentation. Used in clinical longevity trials under medical guidance.

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The Breakdown

QUICK ANSWERS

Do I need to load?
Will it cause bloating?
Safe for kidneys?

+ 4 more questions

DOSE-RESPONSE CURVE

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