Pyruvate (Calcium Pyruvate)

The Krebs cycle intermediate with weight loss hype. Evidence is mixed, so set expectations accordingly.

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Verdict

3/10 Limited

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Evidence

Grade B / 100+ Studies

The No-BS Summary

8 things. 60 seconds. Everything you need.

1

WHAT IT DOES

The Krebs cycle intermediate with weight loss hype

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2

DOES IT WORK?

3/10 Limited. Central to energy metabolism but oral supplementation shows minimal fat loss effects at reasonable doses. High doses needed and cause GI issues.

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3

HOW MUCH TO TAKE

Follow label

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4

COST

$25-60/month depending on brand and form.

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5

FIRST 24 HOURS

Don't expect miracles on day one. It's building in your system.

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6

AFTER A FEW WEEKS

Most people notice something by week 2-3.

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7

SAFETY

Safe for most people. No red flags at normal doses.

8

HOW IT FEELS

Little to no noticeable effect at standard doses. Not worth it for most.

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The Breakdown

QUICK ANSWERS

Do I need to load?
Will it cause bloating?
Safe for kidneys?

+ 4 more questions

DOSE-RESPONSE CURVE

How effective is creatine monohydrate at different doses? Here's what the research shows.