Best Supplements for Weight Loss

Honest assessment: most are overhyped, a few actually help

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Quick Answer

What are the best supplements for weight loss?

The top 3 evidence-based supplements for weight loss are Caffeine (9/10), Fiber (Glucomannan) (5/10), and Protein (7/10). Proven metabolic boost, but tolerance builds

Let's be direct: no supplement will make you lose significant weight without diet and exercise changes. The supplements below have modest evidence for helping at the margins. They're not magic pills.

Actually Supported by Research

Effective Dose100-400mg daily
Time to Effect30-60 minutes

Caffeine increases metabolic rate by 3-11% and enhances fat oxidation during exercise. The effect is real but modest, and tolerance develops over time. Most useful for workout performance.

Best for:Pre-workout energyTemporary metabolic boostFat oxidation during exercise
Effective Dose1g before meals, 3x daily
Time to EffectImmediate fullness, weight loss over weeks

Glucomannan expands in your stomach and creates fullness. Multiple studies show modest weight loss (5-10 lbs over months) when combined with calorie restriction. Must be taken with plenty of water.

Best for:Appetite controlPortion controlFeeling full on fewer calories
Effective Dose20-40g per serving
Time to EffectOngoing

Protein increases satiety more than carbs or fat. It also preserves muscle during calorie restriction, which keeps metabolism higher. Not a weight loss supplement per se, but supports the process.

Best for:Muscle preservationMeal replacementPost-workout recovery

Limited or Mixed Evidence

Effective Dose250-500mg EGCG daily
Time to EffectWeeks to months

Some studies show a small metabolic boost, but results are inconsistent. The effect, if present, is small. Caffeine in green tea may account for most benefits.

Best for:Modest metabolic supportAntioxidant benefits
Effective Dose500mg 2-3x daily
Time to Effect4-8 weeks

Berberine improves insulin sensitivity and may help with weight loss in people with metabolic issues. Effects are modest. Better evidence for blood sugar than weight loss specifically.

Best for:Metabolic healthBlood sugar supportPCOS-related weight issues

Beyond Supplements

  • Calorie deficit remains the foundation - supplements can't replace this
  • Sleep deprivation increases hunger hormones
  • Strength training preserves metabolism during weight loss
  • Stress management - cortisol promotes fat storage

Note: Weight loss supplements have modest effects at best. Focus on sustainable diet and exercise changes. Consult a healthcare provider before starting any supplement regimen.

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