NAD+ (Direct)

Solid evidence for energy. Not a miracle worker, but genuinely useful for the right person.

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Verdict

6/10 Mixed

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Evidence

Grade B / 100+ Studies

The No-BS Summary

8 things. 60 seconds. Everything you need.

1

WHAT IT DOES

The cellular currency itself. Expensive, questionable absorption.

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2

DOES IT WORK?

6/10 Mixed. Direct NAD+ supplementation. Oral absorption debated. IV more effective but impractical. Precursors like NMN may be better oral choice.

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3

HOW MUCH TO TAKE

100-500mg daily

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4

COST

Premium. $50-80/month. Make sure the evidence backs the spend.

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5

FIRST 24 HOURS

Don't expect miracles on day one. It's building in your system.

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6

AFTER A FEW WEEKS

Most people notice something by week 2-3.

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7

SAFETY

Safe for most people. No red flags at normal doses.

8

HOW IT FEELS

Some report energy boost. Absorption is questionable.

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The Breakdown

QUICK ANSWERS

Do I need to load?
Will it cause bloating?
Safe for kidneys?

+ 4 more questions

DOSE-RESPONSE CURVE

How effective is creatine monohydrate at different doses? Here's what the research shows.