Supports liver health and may aid detoxification processes.
Effective Dose
500 mg to 2g daily
Onset
2-4 weeks
Cost
Mid-range
Cycle
No cycling is necessary, but monitoring homocysteine levels is advisable with long-term, high-dose use.
7 things you need to know
What it does
Supports liver health and may aid detoxification processes.
Worth it?
6/10. Methionine is an essential amino acid with potential benefits for liver health and detoxification, but its impact as a supplement at typical doses is subtle. It is better than nothing, but not a first line choice.
How much to take
500 mg to 2g daily
Price
Moderate ($15-30/month)
How fast it works
Takes 2 to 4 weeks to notice
Safety
Check if: individuals with homocystinuria, those with bipolar disorder
What people say
Most users don't report strong subjective effects, but some may experience subtle mood improvements or increased energy levels over time. SAMe form may have more noticeable mood effects.
First isolated in 1922 from casein, a milk protein.
"Most users don't report strong subjective effects, but some may experience subtle mood improvements or increased energy levels over time. SAMe form may have more noticeable mood effects."
Research backing for this ingredient
Some evidence, more research needed
Limited
Not yet
Generally accepted with some debate
"Methionine has a clear biochemical role, and some evidence supports its use for specific liver conditions. However, its effectiveness as a general supplement for the average person is modest."
Methionine is an essential amino acid that plays a crucial role in many bodily functions. It supports liver health by aiding in the breakdown of fats and toxins. SAMe, a derivative of methionine, is used for mood support and joint health.
Products below minimum dose are likely ineffective
When
Any time
How
500 mg to 2g daily
Food
Can be taken with or without food.
Noticeable effects on liver health and mood may take several weeks of consistent supplementation.
No cycling is necessary, but monitoring homocysteine levels is advisable with long-term, high-dose use.
Check for specific interactions.
Methionine is categorized as a amino acid.
Scientific consensus score: 6.5/10.
Evidence quality: MODERATE.
Add Methionine to your stack analyzer or compare it with other ingredients.
Not medical advice. Always consult a healthcare provider.