5-MTHF (Methylfolate)
One of the few supplements that actually delivers. Proven to support methylation with real clinical backing.
Verdict
8/10 Solid
Evidence
Grade B / 100+ Studies
The No-BS Summary
8 things. 60 seconds. Everything you need.
WHAT IT DOES
Folate that works. The form your genes might need.
DOES IT WORK?
8/10 Solid. Good pick. Active methylated folate. Essential if you have MTHFR mutations (40% of population). Folic acid can't help if you can't convert it.
HOW MUCH TO TAKE
400-800mcg daily
COST
Mid-range. $35-50/month. Standard for most people.
FIRST 24 HOURS
Don't expect miracles on day one. It's building in your system.
AFTER A FEW WEEKS
Give it 4-8 weeks for full effects. Patience pays.
SAFETY
One heads-up: overmethylation_risk. Otherwise, you're good.
HOW IT FEELS
Better energy, improved mood, clearer thinking.
QUICK ANSWERS
+ 4 more questions
DOSE-RESPONSE CURVE
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