InteractionsStrong Evidence
47,000+ trials analyzed
59,000+ interactions
Not FDA evaluated

Can You Take Vitamin D and Magnesium Together?

Quick Answer

Yes, and you probably should. Magnesium helps activate vitamin D in your body. Low magnesium can make vitamin D supplementation less effective. Taking them together is not just safe, it's synergistic. Many experts recommend pairing them.

Key Points

  • Magnesium helps activate vitamin D
  • Taking together is synergistic, not problematic
  • Low magnesium can reduce vitamin D effectiveness
  • Consider adding K2 for optimal bone health
  • Timing doesn't matter, consistency does

Detailed Answer

WHY THEY WORK TOGETHER:

Vitamin D needs magnesium to become active. The enzymes that convert vitamin D to its usable form (calcitriol) are magnesium-dependent. Without enough magnesium, your body can't properly use the vitamin D you're taking.

THE RESEARCH:

• Studies show people with adequate magnesium have better vitamin D status • Magnesium supplementation can improve vitamin D levels even without additional D • The combo may be more effective than either alone for bone health

PRACTICAL RECOMMENDATIONS:

• Take them at the same time or separately, doesn't matter • Vitamin D with food (needs fat for absorption) • Magnesium anytime, many prefer evening • Common combo: 2000-5000 IU vitamin D + 300-400mg magnesium

ADD K2 FOR BONUS POINTS:

Vitamin K2 (MK-7) helps direct calcium to bones instead of arteries. The D3 + K2 + Magnesium trio is the gold standard for bone health. Many supplements now combine all three.

Evidence Quality

Strong Evidence

Multiple high-quality studies support this

Key Sources:

  • reviewMagnesium and Vitamin D: Interrelated Nutrients
  • studyMagnesium Status and Vitamin D Metabolism
  • studyD3 + K2 + Magnesium for Bone Health: Clinical Trial

Related Questions

Vitamin D: morning or with a meal containing fat. Magnesium: anytime, but evening can help sleep. Together or separate both work fine.

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About this information: Our recommendations draw from peer-reviewed clinical trials, systematic reviews, and the same medical databases your doctor uses. These statements have not been evaluated by the FDA. Supplements are not intended to diagnose, treat, cure, or prevent any disease.

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