Adenosylcobalamin (B12)
Solid evidence for mitochondrial. Not a miracle worker, but genuinely useful for the right person.
Verdict
7/10 Solid
Evidence
Grade B / 100+ Studies
The No-BS Summary
8 things. 60 seconds. Everything you need.
WHAT IT DOES
Active mitochondrial form of vitamin B12
DOES IT WORK?
7/10 Solid. Good pick. Adenosylcobalamin works in mitochondria for energy production. May be better than cyanocobalamin for some people.
HOW MUCH TO TAKE
Follow label
COST
$25-60/month depending on brand and form.
FIRST 24 HOURS
Don't expect miracles on day one. It's building in your system.
AFTER A FEW WEEKS
Most people notice something by week 2-3.
SAFETY
Safe for most people. No red flags at normal doses.
HOW IT FEELS
Energy support, particularly for mitochondrial function
QUICK ANSWERS
+ 4 more questions
DOSE-RESPONSE CURVE
How effective is creatine monohydrate at different doses? Here's what the research shows.