Periwinkle Extract (Vinpocetine)

European pharmaceutical for brain circulation. Evidence is mixed, so set expectations accordingly.

🏆

Verdict

5/10 Mixed

🎓

Evidence

Grade B / 100+ Studies

The No-BS Summary

8 things. 60 seconds. Everything you need.

1

WHAT IT DOES

European pharmaceutical for brain circulation.

🏆
2

DOES IT WORK?

5/10 Mixed. Semi-synthetic derivative from periwinkle. Increases cerebral blood flow and metabolism. Used as drug in Europe, supplement in US (regulatory gray area). Good for circulation-related cognitive issues.

💊
3

HOW MUCH TO TAKE

Follow label

💰
4

COST

$25-60/month depending on brand and form.

⏱️
5

FIRST 24 HOURS

Don't expect miracles on day one. It's building in your system.

📈
6

AFTER A FEW WEEKS

Most people notice something by week 2-3.

🛡️
7

SAFETY

Safe for most people. No red flags at normal doses.

8

HOW IT FEELS

Improved mental clarity. Better for poor circulation.

2
The Breakdown

QUICK ANSWERS

Do I need to load?
Will it cause bloating?
Safe for kidneys?

+ 4 more questions

DOSE-RESPONSE CURVE

How effective is creatine monohydrate at different doses? Here's what the research shows.