Tributyrin (Butyrate Prodrug)
Solid evidence for colon fuel. Not a miracle worker, but genuinely useful for the right person.
Verdict
6/10 Mixed
Evidence
Grade B / 100+ Studies
The No-BS Summary
8 things. 60 seconds. Everything you need.
WHAT IT DOES
Butyrate that actually reaches your colon. Better delivery than sodium butyrate.
DOES IT WORK?
6/10 Mixed. Triglyceride of butyric acid that delivers butyrate to the colon more effectively than sodium or calcium butyrate. Colon cells primary fuel. Supports gut barrier. Less GI side effects.
HOW MUCH TO TAKE
Follow label
COST
$25-60/month depending on brand and form.
FIRST 24 HOURS
Don't expect miracles on day one. It's building in your system.
AFTER A FEW WEEKS
Most people notice something by week 2-3.
SAFETY
Safe for most people. No red flags at normal doses.
HOW IT FEELS
Improved gut health. Less odor than sodium butyrate.
QUICK ANSWERS
+ 4 more questions
DOSE-RESPONSE CURVE
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