Check Supplement
ProductsIngredientsCheck StackThe Lab
Check Supplement
ProductsIngredientsCheck StackThe Lab
HERBSUPPLEMENT

St. John's Wort

May help improve mood and reduce symptoms of mild to moderate depression.

Effective Dose

300-900 mg of extract daily, standardized to 0.3% hypericin

Onset

2-4 weeks

Cost

Budget

Cycle

It is often recommended to take breaks after several months of continuous use to assess continued need and minimize potential side effects.

MOOD SUPPORT
Grade B20+ studies
Checking sources...
Updated Invalid Date
0.0MIXED
Add to StackCompare

The Quick Version

7 things you need to know

1
2
3
4
5
6
7
1

What it does

May help improve mood and reduce symptoms of mild to moderate depression.

2

Worth it?

6.5/10. St. John's Wort has shown some promise in alleviating symptoms of mild to moderate depression, although its effectiveness can vary. It may be a reasonable option for some individuals, but potential interactions with medications should be carefully considered.

3

How much to take

300-900 mg of extract daily, standardized to 0.3% hypericin

4

Price

Cheap (under $15/month)

5

How fast it works

Takes 2 to 4 weeks to notice

6

Safety

Check if: pregnancy, breastfeeding

7

What people say

Some users report a subtle improvement in mood and a decrease in feelings of sadness or anxiety. Effects are generally mild.

Source Origin

Native to Europe, St. John's Wort now grows wild in many parts of the world, including North and South America, Australia, and Asia.

NATURAL
What It Feels Like

"Some users report a subtle improvement in mood and a decrease in feelings of sadness or anxiety. Effects are generally mild."

Trust Signals

Research backing for this ingredient

C
Evidence Grade: Moderate

Some evidence, more research needed

Studies

Limited

Meta-Analysis

Not yet

Scientific Consensus7/10

Generally accepted with some debate

"There's a reasonable body of evidence suggesting that St. John's Wort can be effective for mild to moderate depression. However, its effectiveness compared to prescription antidepressants is debated, and the risk of drug interactions is a significant concern."

The Breakdown

St. John's Wort is an herbal supplement often used to support mood and reduce symptoms of mild depression. Some studies suggest it can be helpful, but it's important to be aware of potential interactions with other medications.

Dosing Guide
Min: 300 mgEffective: 300-900 mg of extract daily, standardized to 0.3% hypericinMax: 900 mg

Products below minimum dose are likely ineffective

When

Any time

How

300-900 mg of extract daily, standardized to 0.3% hypericin

Food

Take with meals for better absorption and to reduce potential stomach upset.

Onset & Feel
Give It Time

It may take several weeks of consistent use to notice any effects.

Usage Cycle

It is often recommended to take breaks after several months of continuous use to assess continued need and minimize potential side effects.

Mixing Compatibility
Good

Check for specific interactions.

Did You Know?
1

St. John's Wort is categorized as a herb.

2

Scientific consensus score: 7/10.

3

Evidence quality: MODERATE.

Ready to optimize your stack?

Add St. John's Wort to your stack analyzer or compare it with other ingredients.

Add to Stack AnalyzerCompare with Another

Not medical advice. Always consult a healthcare provider.

Explore More Ingredients