May offer mild support for joint comfort.
Effective Dose
200-400mg
Onset
2-4 weeks
Cost
Premium
Cycle
Not typically cycled. Can be taken long-term under medical supervision.
Why not higher?
7 things you need to know
What it does
May offer mild support for joint comfort.
Worth it?
5/10. SAMe might provide modest relief for joint discomfort for some individuals, but its effectiveness is not consistently proven at typical supplement doses. More research is needed.
How much to take
200-400mg
Price
Pricey ($30+/month)
How fast it works
Takes 2 to 4 weeks to notice
Safety
Check if: bipolar disorder, anxiety
What people say
Most users don't report noticeable immediate effects. Some may experience mild mood elevation or increased energy over time.
SAMe is naturally produced in the body and found in all living cells. It was first discovered in Italy in 1952.
"Most users don't report noticeable immediate effects. Some may experience mild mood elevation or increased energy over time."
Research backing for this ingredient
Some evidence, more research needed
Limited
Not yet
Mixed opinions in scientific community
"Research on SAMe for joint health is mixed. Some studies suggest benefits, while others show no significant difference compared to placebo. Dosage and individual response seem to play a significant role."
SAMe is used as a supplement for joint health, and some users report mood benefits. However, scientific evidence is not conclusive, and individual responses can vary. It's important to be aware of potential side effects and interactions.
Products below minimum dose are likely ineffective
When
Any time
How
200-400mg
Food
Take consistently at the same time each day for optimal absorption.
May take several weeks of consistent use to notice any potential effects.
Not typically cycled. Can be taken long-term under medical supervision.
Check for specific interactions.
SAMe (Joints) is categorized as a amino acid.
Scientific consensus score: 5/10.
Evidence quality: WEAK.
Add SAMe (Joints) to your stack analyzer or compare it with other ingredients.
Not medical advice. Always consult a healthcare provider.