May support hormone balance and cognitive function.
Effective Dose
10-50 mg
Onset
Days
Cost
Mid-range
Cycle
Cycling may be beneficial to prevent downregulation of natural hormone production. Consider a cycle of 4-8 weeks followed by a break.
Why not higher?
7 things you need to know
What it does
May support hormone balance and cognitive function.
Worth it?
5/10. Pregnenolone shows promise in supporting hormone balance and cognitive function, but the evidence is preliminary and inconsistent at typical supplement doses. More research is needed to determine its effectiveness, particularly when compared to other well-established alternatives for cognitive support and hormonal health.
How much to take
10-50 mg
Price
Moderate ($15-30/month)
How fast it works
Builds up over days to weeks
Safety
Check if: hormone-sensitive conditions, pregnancy
What people say
Users may report increased energy, improved mood, and enhanced cognitive function. However, experiences can vary widely.
Pregnenolone is naturally synthesized from cholesterol in the adrenal glands, gonads, and brain.
"Users may report increased energy, improved mood, and enhanced cognitive function. However, experiences can vary widely."
Research backing for this ingredient
Some evidence, more research needed
Limited
Not yet
Mixed opinions in scientific community
"While pregnenolone is a precursor to several important hormones and neurotransmitters, its effectiveness as a supplement is debated. The body's complex regulatory mechanisms and varying individual responses contribute to inconsistent results. More research is needed to clarify optimal dosages and specific benefits."
Pregnenolone is a hormone precursor that can be converted into other hormones like DHEA, progesterone, and testosterone. Supplementing with pregnenolone may help support hormone balance and cognitive function, although individual results can vary.
Products below minimum dose are likely ineffective
When
Morning
How
10-50 mg
Food
Take in the morning to align with the body's natural cortisol rhythm.
Effects may be noticeable within a few days to weeks, depending on individual response and dosage.
Cycling may be beneficial to prevent downregulation of natural hormone production. Consider a cycle of 4-8 weeks followed by a break.
Check for specific interactions.
Pregnenolone is categorized as a compound.
Scientific consensus score: 4/10.
Evidence quality: WEAK.
Add Pregnenolone to your stack analyzer or compare it with other ingredients.
Not medical advice. Always consult a healthcare provider.