PQQ
Solid evidence for mitochondrial support (limited evidence). Not a miracle worker, but genuinely useful for the right person.
Verdict
6/10 Mixed
Evidence
Grade C / 6+ Studies
The No-BS Summary
8 things. 60 seconds. Everything you need.
WHAT IT DOES
May support mitochondrial health and energy production, but evidence is limited at typical supplement doses.
DOES IT WORK?
6/10 Mixed. PQQ shows promise in animal and in-vitro studies for mitochondrial biogenesis and antioxidant effects. However, human evidence at realistic supplement doses is weak and inconsistent. Overhyped based on preliminary research.
HOW MUCH TO TAKE
10-20 mg
COST
Mid-range. $35-50/month. Standard for most people.
FIRST 24 HOURS
Don't expect miracles on day one. It's building in your system.
AFTER A FEW WEEKS
Give it 4-8 weeks for full effects. Patience pays.
SAFETY
Few things to check: may interact with blood thinners., insufficient data on long-term safety.. Worth mentioning to your doc.
HOW IT FEELS
Some users report increased energy levels and improved cognitive function, but these effects are not consistently observed and could be placebo.
QUICK ANSWERS
+ 4 more questions
DOSE-RESPONSE CURVE
How effective is creatine monohydrate at different doses? Here's what the research shows.