May provide mild support for pain and inflammation.
Effective Dose
300-600mg
Onset
2-4 weeks
Cost
Mid-range
Cycle
Not required; PEA can be used continuously.
Why not higher?
7 things you need to know
What it does
May provide mild support for pain and inflammation.
Worth it?
5/10. PEA shows some promise for pain and inflammation, but the evidence is not yet strong enough to recommend it over other well-established options. It might be worth considering for those who don't respond well to typical pain relief supplements.
How much to take
300-600mg
Price
Moderate ($15-30/month)
How fast it works
Takes 2 to 4 weeks to notice
Safety
Check if: may interact with blood thinners. consult a doctor if you are on any medications., limited long-term safety data. use with caution for extended periods.
What people say
Users might experience a subtle reduction in discomfort and a general sense of well-being after several weeks. It's generally not associated with strong or immediate effects.
PEA is naturally found in many foods, including egg yolks and peanuts.
"Users might experience a subtle reduction in discomfort and a general sense of well-being after several weeks. It's generally not associated with strong or immediate effects."
Research backing for this ingredient
Some evidence, more research needed
Limited
Not yet
Mixed opinions in scientific community
"While some studies show positive results, many are small or have methodological limitations. More robust research is needed to confirm its efficacy. There is a plausible mechanism of action via the endocannabinoid system."
PEA is a naturally occurring fatty acid amide that is believed to have anti-inflammatory and analgesic properties. It works by interacting with receptors in the endocannabinoid system, which plays a role in regulating pain, inflammation, and mood. Supplementation may help reduce discomfort and promote overall well-being, but results can be subtle and take time.
Products below minimum dose are likely ineffective
When
Any time
How
300-600mg
Food
Can be taken with or without food.
Effects may take several weeks of consistent use to become noticeable.
Not required; PEA can be used continuously.
Check for specific interactions.
Palmitoylethanolamide (PEA) is categorized as a fatty acid.
Scientific consensus score: 5/10.
Evidence quality: WEAK.
Add Palmitoylethanolamide (PEA) to your stack analyzer or compare it with other ingredients.
Not medical advice. Always consult a healthcare provider.