The barrier builder.
Effective Dose
500mg (Oral) / 5% (Topical)
Onset
Days
Cost
Budget
Cycle
As needed
7 things you need to know
What it does
The barrier builder.
Worth it?
10/10. Gold standard active ingredient.
How much to take
500mg (Oral) / 5% (Topical)
Price
Cheap (under $15/month)
How fast it works
Builds up over days to weeks
Safety
Safe for most people at recommended doses
What people say
Skin resilience.
VITAMIN
"Skin resilience."
Research backing for this ingredient
Multiple high-quality studies confirm efficacy
65+
Yes
Strong agreement among researchers
Reduces acne severity and sebum production (Topical)
Comparative RCTs (equivalent to 1% clindamycin)
Reduces rate of new non-melanoma skin cancers (Oral)
Phase 3 RCT (ONTRAC study, n=386)
Improves skin barrier function and reduces hyperpigmentation
Multiple double-blind, split-face RCTs
"Gold standard active ingredient."
The holy grail of skincare. It strengthens the skin barrier, regulates oil, reduces redness, and fades dark spots.
Products below minimum dose are likely ineffective
When
Any time
How
500mg (Oral) / 5% (Topical)
Food
With or without food
Effects build over days to weeks
As needed
Check for specific interactions.
Niacinamide (Vitamin B3) is categorized as a vitamin.
Scientific consensus score: 10/10.
Evidence quality: STRONG.
Add Niacinamide (Vitamin B3) to your stack analyzer or compare it with other ingredients.
Not medical advice. Always consult a healthcare provider.