Methylfolate (5-MTHF)

One of the few supplements that actually delivers. Proven to support folate with real clinical backing.

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Verdict

8/10 Solid

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Evidence

Grade B / 100+ Studies

The No-BS Summary

8 things. 60 seconds. Everything you need.

1

WHAT IT DOES

Active folate. Bypasses MTHFR issues.

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2

DOES IT WORK?

8/10 Solid. Good pick. The active form of folate. Essential for MTHFR gene variants. Better absorbed and utilized than folic acid.

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3

HOW MUCH TO TAKE

See product label

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4

COST

Mid-range. $35-50/month. Standard for most people.

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5

FIRST 24 HOURS

Don't expect miracles on day one. It's building in your system.

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6

AFTER A FEW WEEKS

Give it 4-8 weeks for full effects. Patience pays.

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7

SAFETY

Safe for most people. No red flags at normal doses.

8

HOW IT FEELS

Better energy and mood for some.

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The Breakdown

QUICK ANSWERS

Do I need to load?
Will it cause bloating?
Safe for kidneys?

+ 4 more questions

DOSE-RESPONSE CURVE

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