Histidine may support exercise performance and muscle recovery.
Effective Dose
500mg-3g daily
Onset
2-4 weeks
Cost
Budget
Cycle
Histidine can be taken daily without cycling.
7 things you need to know
What it does
Histidine may support exercise performance and muscle recovery.
Worth it?
6/10. Histidine is an essential amino acid with potential benefits for exercise performance and muscle health, but research is still emerging and typical supplement doses may need to be higher to see significant effects.
How much to take
500mg-3g daily
Price
Cheap (under $15/month)
How fast it works
Takes 2 to 4 weeks to notice
Safety
Check if: people with rare genetic disorders like histidinemia should avoid histidine supplements., those with kidney or liver problems should consult a doctor before supplementing.
What people say
Most people don't report any noticeable sensations when taking histidine. Some athletes might experience improved endurance over time.
Histidine was first isolated from sturgeon sperm in 1896 by German physician Albrecht Kossel.
"Most people don't report any noticeable sensations when taking histidine. Some athletes might experience improved endurance over time."
Research backing for this ingredient
Some evidence, more research needed
Limited
Not yet
Mixed opinions in scientific community
"While histidine has a clear biochemical role, the evidence supporting its benefits at typical supplement doses is still developing. More research is needed to confirm its efficacy for specific applications."
Histidine is an essential amino acid that plays a role in protein synthesis, antioxidant defense, and immune function. Supplementation may help improve exercise performance and muscle recovery, although more research is needed.
Products below minimum dose are likely ineffective
When
Any time
How
500mg-3g daily
Food
Can be taken with or without food.
It may take several weeks of consistent supplementation to notice any effects on exercise performance or muscle recovery.
Histidine can be taken daily without cycling.
Check for specific interactions.
Histidine is categorized as a amino acid.
Scientific consensus score: 5/10.
Evidence quality: MODERATE.
Add Histidine to your stack analyzer or compare it with other ingredients.
Not medical advice. Always consult a healthcare provider.