Betaine (TMG)
Solid evidence for targeted benefits. Not a miracle worker, but genuinely useful for the right person.
Verdict
6/10 Mixed
Evidence
Grade B / 100+ Studies
The No-BS Summary
8 things. 60 seconds. Everything you need.
WHAT IT DOES
Methyl donor for homocysteine
DOES IT WORK?
6/10 Mixed. Trimethylglycine. Lowers homocysteine, supports methylation.
HOW MUCH TO TAKE
500-3000mg daily
COST
Budget-friendly. $20-35/month for quality brands.
FIRST 24 HOURS
Don't expect miracles on day one. It's building in your system.
AFTER A FEW WEEKS
Give it 4-8 weeks for full effects. Patience pays.
SAFETY
Safe for most people. No red flags at normal doses.
HOW IT FEELS
May improve exercise performance
QUICK ANSWERS
+ 4 more questions
DOSE-RESPONSE CURVE
How effective is creatine monohydrate at different doses? Here's what the research shows.