May offer mild blood flow benefits, but often overhyped for muscle growth.
Effective Dose
3-6 grams per day, divided into multiple doses.
Onset
Days
Cost
Budget
Cycle
Not necessary, but some users cycle off after several months to maintain sensitivity.
Why not higher?
7 things you need to know
What it does
May offer mild blood flow benefits, but often overhyped for muscle growth.
Worth it?
3.5/10. Arginine is a conditionally essential amino acid involved in various physiological processes. While it's touted for enhancing blood flow and athletic performance, its oral bioavailability is limited, and its effects are often less pronounced than claimed, especially at typical supplement doses.
How much to take
3-6 grams per day, divided into multiple doses.
Price
Cheap (under $15/month)
How fast it works
Builds up over days to weeks
Safety
Check if: individuals with herpes simplex virus (may trigger outbreaks)., those with kidney or liver problems.
What people say
Some users report a slight increase in muscle pump during workouts and improved blood flow. Others may not notice any significant effects.
First isolated from a lupin seedling extract in 1886.
"Some users report a slight increase in muscle pump during workouts and improved blood flow. Others may not notice any significant effects."
Research backing for this ingredient
Several studies show positive results
65+
Yes
Mixed opinions in scientific community
Reduces blood pressure in hypertensive individuals
Meta-analysis of 11 RCTs
Improves mild-to-moderate erectile dysfunction
Systematic review of 10 RCTs
Enhances aerobic and anaerobic exercise performance
Meta-analysis of 15 studies
"While arginine plays a role in nitric oxide production, its effectiveness as a supplement is debated due to bioavailability issues. Some studies show benefits for specific populations (e.g., those with cardiovascular issues), but results are inconsistent for healthy individuals."
Arginine is an amino acid that the body uses to produce nitric oxide, which helps relax blood vessels and improve blood flow. Supplementation may benefit cardiovascular health and exercise performance, but its effectiveness is limited by its bioavailability.
Products below minimum dose are likely ineffective
When
Any time
How
3-6 grams per day, divided into multiple doses.
Food
Can be taken with or without food. Some users prefer taking it before workouts.
Noticeable effects, if any, typically require consistent supplementation for several days to weeks.
Not necessary, but some users cycle off after several months to maintain sensitivity.
Check for specific interactions.
Arginine is categorized as a amino acid.
Scientific consensus score: 5/10.
Evidence quality: MODERATE.
Add Arginine to your stack analyzer or compare it with other ingredients.
Not medical advice. Always consult a healthcare provider.