VS BATTLE
47,000+ trials analyzed
59,000+ interactions
Not FDA evaluated

Morning vs Evening Supplements

Does timing actually matter?

TL;DR

For most supplements, timing matters less than consistency. Exceptions: B vitamins (morning. can energize), Magnesium (evening. calming), Melatonin (30 min before bed). Take fat-soluble vitamins with food whenever you eat.

AMorning

Wins

  • +Easier to build into existing routine
  • +B vitamins may energize some people
  • +Get it done. no forgetting later
  • +Iron absorbs better morning fasted
  • +Probiotics: stomach acid lowest AM

Loses

  • -Some supplements are calming (counterproductive)
  • -Empty stomach can cause nausea (fish oil)
  • -May interfere with coffee absorption

BEvening

Wins

  • +Magnesium has calming effect for sleep
  • +Less rushed than mornings
  • +Better for sleep-supporting supplements
  • +Some minerals absorb better with dinner

Loses

  • -Easier to forget
  • -B vitamins may interfere with sleep for some
  • -Iron shouldn't be taken with calcium (often in dinner)

The Verdict

Consistency beats timing for almost everything

Unless a supplement specifically affects sleep or energy, take it when you'll remember. Studies show timing differences are marginal compared to the benefit of just taking them consistently. Overthinking timing is a recipe for quitting.

Choose Morning When:

  • B-complex vitamins (may energize)
  • Rhodiola (stimulating adaptogen)
  • Iron (if taking on empty stomach)
  • Probiotics (lowest stomach acid)
  • You have a solid morning routine

Choose Evening When:

  • Magnesium (especially glycinate. calming)
  • Melatonin (30 min before bed)
  • L-theanine (if using for sleep)
  • Zinc (if it bothers your stomach. take with dinner)
  • Your mornings are chaotic

The Bottom Line

Magnesium = evening. B vitamins = morning. Everything else = whenever you'll actually take it.

More VS Battles

About this information: Our recommendations draw from peer-reviewed clinical trials, systematic reviews, and the same medical databases your doctor uses. These statements have not been evaluated by the FDA. Supplements are not intended to diagnose, treat, cure, or prevent any disease.

Moderate Evidence

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