ComparisonModerate Evidence
47,000+ trials analyzed
59,000+ interactions
Not FDA evaluated

Are Expensive Supplements Worth the Money?

Quick Answer

Sometimes. Third-party tested brands (Thorne, NOW, Life Extension) cost more but verify contents. Cheap supplements often fail purity tests. For basics like vitamin D or magnesium, generic is usually fine. For fish oil, probiotics, and herbs, quality matters more.

Key Points

  • Third-party testing is worth paying for
  • Fish oil and probiotics: quality matters more
  • Basic vitamins: generic usually fine
  • Better forms (ubiquinol, glycinate) justify higher prices
  • Cheap supplements often fail independent testing

Detailed Answer

WHEN QUALITY MATTERS:

• Fish Oil: Cheap oil is often oxidized (rancid). Bad for you instead of good. Pay for IFOS-certified. • Probiotics: Cheap ones often have dead bacteria. Refrigerated or spore-based worth the premium. • Herbs/Botanicals: Standardization and purity vary wildly. Third-party testing essential. • CoQ10: Ubiquinol costs more than ubiquinone but absorbs 3-4x better. • Protein: Quality varies. Third-party tested brands verify protein content matches label.

WHEN GENERIC IS FINE:

• Vitamin D3: Molecule is identical. Cheap brands work. • Creatine Monohydrate: CreaPure is nice but regular monohydrate is fine. • Basic minerals (without complex forms): Magnesium oxide is cheap and works for laxative effect. But glycinate costs more and absorbs better. • Vitamin C: Ascorbic acid is ascorbic acid.

WHAT YOU'RE PAYING FOR:

• Third-party testing (USP, NSF, ConsumerLab) • Actual ingredient amounts matching label • Proper manufacturing and storage • Better absorption forms • Research on specific strains/extracts

Evidence Quality

Moderate Evidence

Some quality studies, more research helpful

Key Sources:

  • reviewConsumerLab Independent Supplement Testing
  • reviewSupplement Quality Variation: Industry Analysis

Related Questions

Thorne, NOW Foods, Life Extension, and Jarrow have good reputations. Look for USP, NSF, or ConsumerLab verification. Amazon reviews mean nothing for quality.

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About this information: Our recommendations draw from peer-reviewed clinical trials, systematic reviews, and the same medical databases your doctor uses. These statements have not been evaluated by the FDA. Supplements are not intended to diagnose, treat, cure, or prevent any disease.

Moderate Evidence

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