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Active B12 with L-5-MTHF Lozenges

Two active B12 coenzyme forms (methylcobalamin + adenosylcobalamin) with methylfolate, sublingual. Designed by the MTHFR expert (Dr. Ben Lynch). This is what a biochemist would design if they wanted the most complete B12 supplement possible.

8.5/10
EXCELLENT

Dual-form B12 (adenosyl + methyl) with methylfolate in a sublingual lozenge. Dr. Ben Lynch designed this for MTHFR variants who need both B12 coenzyme forms. The most biochemically sophisticated B12 product available.

2 ingredientsLOZENGE60 servings
We'd recommend this
Evidence
10.0
Dosing
8.0
Synergy
9.0
Check My Stack
Whenmorning

B12 supports energy. Take in the morning.

Foodwithout food

Sublingual absorption. Dissolve under tongue away from food.

SafetyAll clear

If sensitive to methylation, start with half a lozenge.

ResearchStrong evidence

Both B12 coenzyme forms are well-studied. Methylfolate for MTHFR is established.

What We Like

  • Two active B12 forms: methylcobalamin + adenosylcobalamin.
  • Methylfolate for MTHFR-safe folate delivery.
  • Sublingual bypasses gut absorption issues.
  • Dr. Ben Lynch formulation (MTHFR expert).
  • 800mcg doses are therapeutic without being excessive.

Watch Out For

  • Niche product for people who understand methylation.
  • Both active B12 forms may be too much methylation for some.
  • Premium pricing.

Ingredient Breakdown

1 clinical1 adequate
Clinical Adequate Underdosed Overdosed|Bar = % of clinical dose
IngredientDoseStatusvs. Clinical
Vitamin B1210.0

Adenosylcobalamin + Methylcobalamin (50:50)

800 mcgADEQUATE
80%
800 mcg

of 1000mcg

ADEQUATE
80%
Folate10.0

L-5-MTHF Methylfolate

800 mcg DFECLINICAL
100%
800 mcg DFE

of 800mcg

CLINICAL
100%
In our database (click to learn more) Not yet reviewed

Our Analysis

Best For

People with MTHFR variants.Those with B12 deficiency.Vegetarians and vegans.Older adults with B12 absorption issues.

Skip This If

People who over-methylate easily (try hydroxocobalamin instead).

Time to Feel

1-2 weeks if deficient. Energy improvement can be rapid.

Value

GOOD

How to take: No cycling needed.

Personalized Deep Analysis

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