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Pure Encapsulations
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MOODPure Encapsulations

Emotional Wellness

Saffron extract (affron) has 8+ clinical trials showing mood improvement comparable to low-dose Prozac. 30mg is the exact studied dose. P-5-P B6 and methylfolate support serotonin synthesis. This is mood support with actual evidence behind it.

8.0/10
EXCELLENT

Saffron extract (affron) has 8+ clinical trials showing mood benefits comparable to low-dose SSRIs. P-5-P B6 and methylfolate support neurotransmitter synthesis. Evidence-based mood support.

4 ingredientsCapsules30 servings
We'd recommend this
Evidence
9.0
Dosing
8.0
Synergy
8.0
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Whenmorning

Mood support throughout the day.

Foodwith food

Better tolerated with food.

SafetyAll clear

Not a replacement for prescribed antidepressants. Consult doctor if on SSRIs.

ResearchStrong evidence

Saffron (affron) has one of the strongest evidence bases of any mood supplement. 8+ RCTs.

What We Like

  • Saffron (affron) has 8+ RCTs for mood with consistent positive results.
  • 30mg matches the clinical dose exactly.
  • P-5-P is the active form of B6 (directly supports serotonin synthesis).
  • Methylfolate for MTHFR-safe neurotransmitter support.

Watch Out For

  • Premium Pure Encapsulations pricing.
  • Only 30 servings.
  • Not a replacement for clinical treatment of depression.

Ingredient Breakdown

1 clinical2 underdosed
Clinical Adequate Underdosed Overdosed|Bar = % of clinical dose
IngredientDoseStatusvs. Clinical
Saffron Extract

affron, 3.5% Lepticrosalides

30 mgCLINICAL
100%
30 mg

of 30mg

CLINICAL
100%
Folate10.0

5-MTHF Methylfolate

400 mcg DFEUNDERDOSED
50%
400 mcg DFE

of 800mcg

UNDERDOSED
50%
Vitamin B1210.0

Methylcobalamin

500 mcgUNDERDOSED
50%
500 mcg

of 1000mcg

UNDERDOSED
50%
Vitamin B6

P-5-P Pyridoxal-5-Phosphate

20 mgOVERDOSED
200%
20 mg

of 10mg

OVERDOSED
200%
In our database (click to learn more) Not yet reviewed

Our Analysis

Best For

People with mild mood concerns.Those wanting natural mood support alongside therapy.People with seasonal mood changes.

Skip This If

Those with severe depression (see a doctor).Pregnant women (saffron at high doses is contraindicated).

Time to Feel

2-4 weeks for initial effects. Full benefit at 8 weeks.

Value

FAIR

How to take: Can use daily long-term. Effects build over 4-8 weeks.

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