Check Supplement
Check My StackMy Health
All Products
Microbiome Labs MegaSporeBiotic
SPECIMEN #MICROBIO
Verified
PROBIOTICSMicrobiome Labs

MegaSporeBiotic

The practitioner-favorite spore probiotic. 5 Bacillus strains with near 100% stomach acid survival. Published clinical trial showing microbiome diversity increase in 30 days. Start slow though, because die-off reactions are real.

8.5/10
EXCELLENT

The practitioner-favorite spore-based probiotic. 5 Bacillus strains that survive stomach acid, don't need refrigeration, and have clinical research. The standard for spore probiotics.

5 ingredientsCapsules30 servings
We'd recommend this
Evidence
9.0
Dosing
8.0
Synergy
9.0
Check My Stack
Whenwith meals

Bile salts from food activate spore germination.

Foodwith food

Spores germinate better in the presence of bile (triggered by food).

SafetySome cautions

Start with 1 capsule every other day. Die-off reactions possible in first 1-2 weeks.

ResearchStrong evidence

Published clinical trial showing microbiome diversity increase. Individual strains well-characterized.

What We Like

  • Spore-based strains have near 100% survival through stomach acid.
  • No refrigeration needed. Shelf-stable for years.
  • HU36 produces antioxidants (carotenoids) in the gut.
  • Clinical study showed significant microbiome diversity improvement.
  • Individual strain CFU counts disclosed.

Watch Out For

  • Practitioner-only distribution makes it harder to buy.
  • Premium price.
  • Only Bacillus strains (no Lactobacillus or Bifidobacterium).

What We Analyzed

MegaSporeBiotic Supplement Facts

Verified Supplement Facts

Every dose checked against clinical research

We analyzed the actual supplement facts panel for this product. Every ingredient dose below was cross-referenced with published clinical trials to determine if it matches what studies actually use.

5 ingredients analyzed

Source: Official product page

Ingredient Breakdown

Clinical Adequate Underdosed Overdosed|Bar = % of clinical dose
IngredientDoseStatusvs. Clinical
Bacillus indicus HU367.0
2 Billion CFU
2 Billion CFU
Bacillus subtilis HU587.0
2 Billion CFU
2 Billion CFU
Bacillus coagulans SC208
2 Billion CFU
2 Billion CFU
Bacillus licheniformis
2 Billion CFU
2 Billion CFU
Bacillus clausii SC109
2 Billion CFU
2 Billion CFU
In our database (click to learn more) Not yet reviewed

Our Analysis

Best For

People who failed with regular probiotics.Those wanting shelf-stable probiotics for travel.IBS and SIBO sufferers.Practitioners' top recommendation.

Skip This If

Immunocompromised (consult doctor).Those sensitive to die-off (start very slow).

Time to Feel

2-4 weeks

Value

FAIR

How to take: Can use daily long-term. Start slow.

Personalized Deep Analysis

See exactly how this fits your health profile. What works for you, what doesn't, and whether you're getting your money's worth.

Unlock with Pro

Taking other supplements too?

Check your full stack for interactions, redundancies, and gaps. Takes 30 seconds.

Check My Stack
0 views