Collagen: Complete Guide
Structural protein for skin, joints, and gut. Actually works for skin elasticity. Takes 2-3 months.
Quick Summary
Structural protein for skin, joints, and gut. Actually works for skin elasticity. Takes 2-3 months. 5-10g hydrolyzed collagen daily. Best form: Hydrolyzed Peptides.
What is Collagen?
Collagen is the most abundant protein in your body (30% of total protein). It provides structure to skin, bones, tendons, and ligaments. Your body makes it, but production drops ~1% per year after 25. Supplements provide amino acid building blocks.
Who Should Consider Collagen?
- Anyone over 30 wanting skin benefits
- People with joint pain or stiffness
- Athletes with connective tissue concerns
- Those recovering from injuries
- People wanting gut lining support
How It Works
Hydrolyzed collagen (peptides) gets broken down into amino acids during digestion, then absorbed. These amino acids (glycine, proline, hydroxyproline) may signal your body to produce more collagen. Not a direct delivery system, but the signal appears to work.
Forms Comparison
Different forms of Collagen have varying absorption rates and best uses. Here's how they compare:
| Form | Bioavailability | Best For |
|---|---|---|
| Hydrolyzed Peptides | 90% | Best absorption. Dissolves in anything. Standard choice. |
| Undenatured Type II | Different mechanism | Joint-specific. Works via immune modulation, not building blocks. |
| Marine (fish) | 85% | Type I dominant. Good for skin. Pescatarian option. |
| Bovine | 85% | Type I and III. Good all-around. Most common. |
Our recommendation: Hydrolyzed Peptides for most people due to superior absorption and tolerability.
Benefits & Evidence
Collagen has 1 strongly-evidenced benefits and 2 moderately-evidenced benefits.
Skin elasticity/hydration
strong evidence2019 meta-analysis: significant improvement vs placebo
Joint comfort
moderate evidenceReduces activity-related joint pain in athletes
Nail/hair strength
moderate evidenceImproved brittle nail syndrome in studies
Gut lining support
emerging evidenceGlycine content may support intestinal barrier
Dosing & Timing
Recommended Doses
Timing
Side Effects & Interactions
Possible Side Effects
- Mild bloating initially. Occasional
- Bad taste (some products). Product-dependent
Interactions to Know
- Vitamin C enhances collagen synthesis (take together)
- Generally safe with all supplements
- No significant drug interactions
Frequently Asked Questions
Both work. Marine is Type I dominant (skin focus). Bovine is Types I and III (skin + gut). Pick based on source preference, not efficacy.
Related Topics
About this information: Our analysis of Collagen is based on peer-reviewed research from PubMed, ClinicalTrials.gov, and NIH databases. These statements have not been evaluated by the FDA. Supplements are not intended to diagnose, treat, cure, or prevent any disease.
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Track it alongside your other supplements for interaction checking.